Biography
Dr. Shane Dillon completed his PhD in 2008 in the laboratory of Dr. David Vetrie, Wellcome Trust Sanger Institute, Cambridge, UK. He subsequently moved to the Department of Microbiology, Trinity College Dublin to work with Professor Charles Dorman on elucidating the role of chromosome and plasmid encoded transcription factors in Salmonella pathogenicity. He subsequently moved to the Centre for Bacterial Cell Biology, Newcastle University, UK in 2012 as a Post-Doctoral Researcher. He then returned to the Department of Microbiology, Trinity College Dublin in 2013 as an Assistant Professor. He is currently appointed as an Assistant Lecturer in Microbiology in the School of Biological and Health Sciences, TUDublin
Qualifications
BA (Mod.) Human Genetics (Trinity College Dublin), Ph.D. Biological Sciences (Cambridge University)
Research Themes
Food and Waterborne Bacteria, Microbial Source Tracking, Salmonella Pathogenicity
Keywords
Salmonella, E. coli, Microbial Genomics, Next-Gen DNA Sequencing, RNA-Seq, Chromatin Immunoprecipitation
Key Publications
Fitzgerald S, Dillon SC, Chao TC, Wiencko HL, Hokamp K, Cameron AD, Dorman CJ. Re-engineering cellular physiology by rewiring high-level global regulatory genes. Sci Rep. 2015, 5:17653.
Paytubi S, Aznar S, Madrid C, Balsalobre S, Dillon SC, Dorman CJ, Juárez A. A novel role for antibiotic resistance plasmids in facilitating Salmonella adaptation to non-host environments. Environ Microbiol. 2014, 16(4):950-62.
Dillon SC, Espinosa E, Hokamp K, Ussery DW, Casadesús J, Dorman CJ. LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium. Mol Microbiol. 2012, 85(6):1072-89.
Kröger C, Dillon SC, Cameron ADS, Papenfort K, Sivasankaran SK, Karsten Hokamp K, Chao Y, Sittka A, Hébrard M, Händler K, Colgan A, Leekitcharoenphon P, Langridge GC, Lohan AJ, Loftus B, Lucchini S, Ussery DW, Dorman CJ, Thomson NR, Vogel J, Hinton JCD: Global transcriptional mapping, RNA polymerase distribution and the unique sRNA complement of the model pathogen Salmonella enterica serovar Typhimurium. Proc Natl Acad Sci U S A. 2012, 109(20): E1277-86.
Dillon SC, Cameron AD, Hokamp K, Lucchini S, Hinton JC, Dorman CJ. Genome-wide analysis of the H-NS and Sfh regulatory networks in Salmonella Typhimurium identifies a plasmid-encoded transcription silencing mechanism. Mol Microbiol. 2010, 76(5):1250-65.
Dillon SC, Dorman CJ. Bacterial nucleoid-associated proteins, nucleoid structure and gene expression. Nat Rev Microbiol. 2010 8(3):185-95.
Professional Memberships
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Member of the Society for General Microbiology
External Activities/Outreach
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Reviewer for the Journals Nucleic Acids Research, Molecular Microbiology and Microbiology